Plain-English translation of NCT07780929 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Psoriasis research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new experimental skin ointment called XJH05 to see if it can help improve plaque psoriasis—a chronic skin condition marked by thick, scaly red patches. The study will compare how well XJH05 works compared to a standard psoriasis treatment (calcipotriol) when both are applied directly to affected skin areas twice daily for four weeks.
Plaque psoriasis affects most psoriasis patients and can be very difficult to manage with currently available treatments. Even though many topical creams exist, psoriasis remains a lifelong condition with limited options, so researchers are investigating new medications like this one to help patients achieve better symptom relief.
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You will be asked to apply either the new or a standard psoriasis cream (calcipotriol) to your affected skin areas twice per day for four weeks. The study team will take photos of your skin at the start and end of the four weeks to track changes. At the end, you will be evaluated using standard scoring tools to measure how much your symptoms improved and how itchy your skin is.
AI-generated summary from trial data · Aug 27, 2026 · Not medical advice
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