Electric pulses to treat cancer that has returned in the pelvis

The PELFIRE Study is testing a treatment called irreversible electroporation (IRE) — a procedure that uses precisely controlled electric pulses to destroy cancer cells. This study includes patients whose cancers have returned in the pelvic area (the lower part of your belly) and who cannot have surgery or radiation therapy. Researchers want to learn whether this treatment can help control the cancer and improve outcomes.

When cancer comes back in the pelvis after initial treatment, options are often limited because surgery and radiation may be too risky or not possible. This trial exists to see whether electric pulse therapy could offer patients like you another effective choice when standard treatments aren't suitable.