Plain-English translation of NCT07796074 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether bupivacaine—a numbing medication—injected around a nerve at the back of your head (called the greater occipital nerve) can help reduce chronic headaches that started after a head injury. You would receive one injection, and then track your headaches for two months to see if the treatment helps. Researchers will compare three groups: those who receive no active medication, a very low dose, and a standard dose to find out which works best.
Many veterans develop long-lasting headaches after head injuries, and current headache treatments don't work well for everyone or can cause unwanted side effects. This treatment is simple, inexpensive, and has helped people with other types of headaches, so doctors want to see if it can safely help veterans with post-injury headaches too.
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You will visit the clinic to receive one injection of numbing medication around the nerve at the back of your head—this is a quick, outpatient procedure. After the injection, you'll go home and keep a headache diary for two months, writing down how often and how severe your headaches are. This allows researchers to track whether the treatment reduces your headache burden over time.
AI-generated summary from trial data · Sep 4, 2026 · Not medical advice
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