Recruiting

Testing a new cancer treatment for advanced solid tumors

Plain-English translation of NCT07807956 on ClinicalTrials.gov ↗ · Source last updated October 2026 · Translation generated October 2026 · How we translate trials

Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.

This is one of the first times this treatment has been tested in people.

What is this trial?

This is a first-in-human study testing a new investigational medication called in adults with advanced solid tumors — cancers that have spread or are difficult to treat. The trial will evaluate whether this medication is safe, how your body processes it, and whether it helps slow or stop cancer growth. The study has two phases: the first explores different dose levels across various cancer types, and the second focuses on finding the best dose for people with non-small cell lung cancer.

Advanced cancers are life-threatening and current treatments don't work well for everyone. This medication is being developed because researchers believe it may offer a new option for people with these hard-to-treat cancers.

Do you qualify?

You likely qualify if…

you have been diagnosed with an advanced solid tumor (such as lung, colorectal, pancreatic, gastric, ovarian, or head and neck cancer)
your cancer can be seen and measured on imaging or medical tests
you are in good enough health to tolerate treatment (generally able to do light activities)
you have not had another active cancer within the past 3 years

You likely don't qualify if…

you have untreated cancer that has spread to your brain or around your spinal cord
you have a history of lung inflammation or scarring (interstitial lung disease or pneumonitis) that required steroid treatment
you have had multiple different cancers, unless they were treated long ago and are considered low risk
you have certain types of ovarian cancer other than high-grade serous ovarian cancer

What participation looks like

You would receive the medication by intravenous infusion at a hospital or clinic as part of a study lasting up to 4 years. You'll attend regular clinic visits for medical check-ups, blood tests, imaging scans, and discussions about any side effects you're experiencing. The trial involves more frequent visits and testing than standard cancer care, and you'll complete questionnaires to help researchers understand how the treatment is affecting you.

Testing a new cancer treatment for advanced solid tumors

What is this trial?

Do you qualify?

What participation looks like

Trial locations(3 sites)