Plain-English translation of NCT07814222 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a new imaging scan called Al[¹⁸F]F-NOTA-folate PET to see if it can better diagnose two serious heart conditions: cardiac sarcoidosis (inflammation of the heart muscle) and infective endocarditis (bacterial infection of heart valves). Researchers will give you this new tracer and take special PET images of your heart to see how well the scan can identify these conditions compared to standard tests you'd normally receive.
Doctors currently struggle to reliably diagnose these two heart conditions early, which can delay treatment and lead to serious complications. This trial is testing whether this new imaging approach can provide clearer, faster answers so patients get the right treatment sooner.
You likely qualify if…
You likely don't qualify if…
If you have suspected cardiac sarcoidosis, you'll come to the hospital for a PET imaging scan using the new tracer, and then return for a second scan after you start treatment with immune-suppressing medication. If you have suspected valve infection, you'll have one PET imaging scan. Healthy volunteers will have one scan. All your other medical decisions and treatments will continue as normal — this study won't change your regular care.
AI-generated summary from trial data · Oct 12, 2026 · Not medical advice
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