Plain-English translation of NCT07823101 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers at Johns Hopkins University are studying whether ultrasound and MRI imaging can help doctors detect swallowing and speech difficulties in people with inclusion body myositis—a rare muscle disease that weakens muscles over time. The study will compare imaging results between people with inclusion body myositis, people with other muscle diseases, people with motor neuron diseases like ALS, and healthy volunteers. This research aims to find the best imaging tools to spot these problems early and monitor how they progress.
Swallowing and speech problems are common in inclusion body myositis and can seriously affect quality of life, but doctors currently lack reliable imaging tools to detect and measure these problems early. This trial seeks to determine whether ultrasound and MRI can serve as better diagnostic markers to help clinicians identify and track these complications sooner.
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If you qualify, you will come to Johns Hopkins University for imaging appointments where you will have ultrasound and MRI scans of the muscles involved in swallowing and speech. You will need to lie still for these scans, which typically take about 30 minutes or longer. The study involves 30 total participants across different groups (people with IBM, other muscle diseases, motor neuron diseases, and healthy controls), and while a specific time commitment is not detailed, imaging visits are non-invasive and painless.
AI-generated summary from trial data · Sep 16, 2026 · Not medical advice
United States
Sponsor
Johns Hopkins University
Enrollment target
~30 participants
Started
October 2026
Primary completion
December 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in September 2026.
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Central contact
Joseph D Niang, B.A.
the Johns Hopkins School of Medicine
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