Plain-English translation of NCT07824089 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research looks at whether regular exercise can help people with alcohol use disorder and alcohol-related liver disease reduce their drinking and heal their livers. Scientists believe exercise might work by changing a natural protein in your body called FGF21, which affects how your muscles and liver work. The trial will compare people who do a supervised home-based cycling program for 12 weeks against people who continue their usual care without structured exercise.
People with alcohol-related liver disease often struggle with heavy drinking, weak muscles, low energy, and continued liver damage. There are limited treatment options beyond standard care, so researchers want to see if regular exercise could be a safe and effective way to help people drink less and improve their muscle strength and liver health.
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If you are enrolled, you will be randomly placed into one of two groups. One group will receive standard medical care plus a 12-week home-based cycling program three days a week (about 60 minutes per session), with remote monitoring and fitness tests at Cleveland Clinic. The other group will continue their usual care without the structured exercise program. All participants will have blood tests, muscle assessments, and other tests to measure changes in drinking, liver health, muscle strength, and fatigue over the study period.
AI-generated summary from trial data · Sep 17, 2026 · Not medical advice
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