Plain-English translation of NCT07832578 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing whether rivaroxaban, a blood thinner, combined with aspirin works better than aspirin alone to protect people with severe leg blood flow problems. The study will follow you for 6 months to see if the medication combination can prevent serious complications like amputation, heart attack, or stroke.
People with severe leg blood flow problems caused by diabetes and other conditions face a high risk of losing their limbs or having heart and stroke events. This trial wants to know if adding this medication to standard aspirin treatment can better prevent these life-changing complications.
You likely qualify if…
You likely don't qualify if…
You will visit the hospital for baseline tests including blood work, ultrasound imaging of your leg arteries, and walking distance measurements. Then you'll be randomly assigned to take either the medication combination or aspirin alone for 6 months. You'll return for follow-up visits at set intervals where doctors will check your leg healing, blood work, side effects, and overall health, and ask about your quality of life.
AI-generated summary from trial data · Oct 12, 2026 · Not medical advice
Pakistan