Testing a Natural Supplement to Support Brain Health in Alzheimer's Disease

This trial is testing Urolithin A (Mitopure®), a natural substance produced by your gut after eating pomegranates, nuts, and berries, to see if it can help people with Alzheimer's disease or early memory problems. Researchers believe this medication may help brain cells work better by boosting energy production in the mitochondria—the 'power plants' of your cells. The study will look at whether this treatment can slow cognitive decline and reduce harmful proteins that build up in the brains of people with Alzheimer's.

Alzheimer's disease damages the brain's ability to clear out harmful proteins, and one reason this happens may be that brain cells don't have enough energy to do the cleanup work. This medication is being tested because early research in animals and lab studies suggests it could give brain cells the energy boost they need to protect against memory loss.