Recruiting

Plant-Based Supplement for Hot Flashes During Menopause

Plain-English translation of NCT07863973 on ClinicalTrials.gov ↗ · Source last updated October 2026 · Translation generated October 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This 12-week study is testing a plant extract-based dietary supplement to see if it can reduce hot flashes and night sweats in women experiencing late perimenopause or early postmenopause. About 120 women will participate, and half will receive the medication while the other half receive a placebo (a pill with no active ingredients). Researchers will track hot flash frequency and severity, as well as how the treatment affects sleep, mood, and overall quality of life.

Hot flashes and night sweats are among the most bothersome symptoms of menopause, and many women are looking for effective alternatives to traditional hormone treatments. This trial is testing whether this plant-based supplement could offer a natural option to help manage these symptoms and improve women's quality of life during this transition.

Do you qualify?

You likely qualify if…

you are a woman aged 42 to 60 years old
you are in late perimenopause or early postmenopause (no period for at least 3 months but no more than 10 years)
you experience at least five moderate or severe hot flashes each day
your body mass index is 35 kg/m² or lower
you are willing to take a daily pill for 12 weeks and attend six in-person visits

You likely don't qualify if…

you have a serious uncontrolled medical condition
you are currently taking medications that could interfere with this study's results
you are allergic to or cannot tolerate any ingredients in the study product
you are enrolled in another clinical trial at the same time
you have concerns about your ability to follow the study plan for 12 weeks

What participation looks like

You would visit the clinic six times over 14 weeks—starting with a 2-week screening period, then 12 weeks of treatment. Each day, you'd take either the plant-based supplement or a placebo pill. You'll keep a daily diary to record your hot flashes and night sweats, and complete questionnaires about your symptoms, sleep, mood, and quality of life. The clinic will also measure your body composition and collect blood samples at the beginning and end of the study to check various health markers.

AI-generated summary from trial data · Oct 12, 2026 · Not medical advice

Trial locations(1 site)

Spain

European Institute Of Exercise and Health, Elche, Alicante