Testing a Brain-Computer Interface Communication Device for ALS

This trial is testing the Cognixion ONE, a brain-computer interface communication device designed to help people with ALS (amyotrophic lateral sclerosis) communicate when their speech becomes impaired. The device uses brain signals captured by sensors worn on the scalp, combined with either augmented-reality glasses or a regular screen, to let you select words and have a conversation. Researchers want to see how well this new technology works compared to eye-tracking communication devices you may already be using.

As ALS progresses, many people lose the ability to speak but retain full mental clarity. While eye-tracking communication devices help some people, they don't work for everyone—especially as the disease advances and eye control becomes difficult. This trial tests whether a brain-based communication system could offer another option when other methods stop working.