Plain-English translation of NCT07913074 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new eye drop called TB0001 (pregabalin ophthalmic solution) to see if it can lower the pressure inside your eye as effectively as timolol, a standard glaucoma medication that many people already use. You would use the medication once daily for 28 days, and researchers would measure your eye pressure and monitor for any side effects to determine the best dose for future studies.
Glaucoma and high eye pressure damage the eye over time, and doctors need new treatment options that work well and are easy for patients to tolerate. This trial explores whether this new medication might offer patients another safe choice for managing their eye pressure.
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You will be randomly assigned to receive one of three different strengths of the new eye drop or the standard timolol treatment. For 28 days, you will instill drops into your study eye once in the morning and once in the evening (one will be the active medication and one will be a placebo to keep the study blinded). You will have office visits where researchers will measure your eye pressure, examine your eye health, and ask about any side effects you may have experienced.
AI-generated summary from trial data · Nov 8, 2026 · Not medical advice
United States