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Prostate Cancer

June 2026 Research Brief

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Trials

AR pathwayPh 2
Leuprolide with or without 177Lu-PSMA-617 and abiraterone treats newly diagnosed or recurrent low-volume metastatic prostate cancer.

Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial

Mayo ClinicPosted: Jun 2026NCT07650240
Clinical Trials Referral Officemayocliniccancerstudies@mayo.edu
Biomarker
AI tool combining blood tests, labs, and ultrasound diagnoses prostate cancer in patients with borderline PSA levels.

Intelligent Screening and Precision Diagnosis of Prostate Cancer Based on Multimodal Data

Guangxi Medical UniversityPosted: Jun 2026NCT07631806
Drug / intervention
Message framing strategies encourage cancer and diabetes screening uptake in Chilean patients.

Nudging Preventive Screening Via Message Framing and Bundling

University of ChilePosted: Jun 2026NCT07644910
Daniel Schwartz Associate Professor, Department of Industrial Engineering, Ph.D. Behavioral Decisiondaschwar@dii.uchile.cl
Drug / interventionPh 2
Risk-adapted treatment approach for metastatic hormone-sensitive prostate cancer with potential treatment reduction.

RISK-ADAPT Protocol in Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

Georgetown UniversityPosted: Jun 2026NCT07645326
DiagnosticsPh 3
68Ga-NYM032 PET/CT imaging detects prostate cancer recurrence.

This Study Evaluates the Diagnostic Performance and Safety of 68Ga-NYM032 PET/CT Imaging in Patients With Suspected Recurrence of Prostate Cancer.

Norroy Bioscience Co., LTDPosted: Jun 2026NCT07649122
Surgery
Vanquish water vapor ablation treats intermediate-risk Grade Group 3 prostate cancer.

Water Vapor Ablation for Grade Group 3 Prostate Cancer

Francis Medical Inc.Posted: Jun 2026NCT07652164
Drug / intervention
Spinal versus general anesthesia compared for open prostate removal surgery complications.

Spinal Versus General Anesthesia in Open Simple Prostatectomy

Hitit UniversityPosted: Jun 2026NCT07643415
Mustafa Serdar Çağlayanserdar.09.09@hotmail.com
AR pathwayPh 2
PSMA PET/CT-guided radiation combined with darolutamide treats metastatic hormone-sensitive prostate cancer.

PSMA PET/CT-Guided SBRT Plus Darolutamide in mHSPC

West China HospitalPosted: Jun 2026NCT07649421
Hao Zeng, MD, PhDkucaizeng@163.com
Surgery
Aquablation therapy treats localized prostate cancer.

WATER IV PCa (AS Sub-study)

PROCEPT BioRoboticsPosted: Jun 2026NCT07650448
Radiation
Study tracks lymphedema development and impact in men after prostate cancer treatment.

Risk Factors, Incidence, and Progression of Lymphedema Among Men With Prostate Cancer. The AWARE Cohort

Rigshospitalet, DenmarkPosted: May 2026NCT07607431

Showing trials with activity in the past 30 days. See the full Prostate Cancer research landscape →

Recently completed · awaiting results

ChemotherapyPh 2
Olaparib maintenance therapy after chemotherapy aims to control aggressive variant prostate cancer in men.

Study of Olaparib Maintenance Following Cabazitaxel-Carbo in Men With AVPC

M.D. Anderson Cancer CenterEst. completion: Jun 2026NCT03263650
AR pathwayPh 1
Abemaciclib and darolutamide combined with hormone therapy treat metastatic and advanced prostate cancer in men.

Neo-DAB: Darolutamide and Abemaciclib in Prostate Cancer

Praful Ravi, MB BCHir, MRCPEst. completion: Jul 2025NCT05617885
Drug / intervention
Socio-aesthetics wellness care improves quality of life and reduces pain and anxiety in cancer patients.

Evaluation of the Medical Service by Socio-aesthetics in Oncology

Centre Hospitalier de ValenceEst. completion: Jun 2026NCT06035731
Surgery
Mobile app education reduces preoperative anxiety and improves outcomes for men undergoing prostate surgery.

Effect of Education to be Provided to Patients to Undergo TURP With Mobile Application on Patient Outcomes

Tarsus UniversityEst. completion: Apr 2026NCT06687538

Condition guide

Prostate Cancer — the full picture

Research landscape, trial types, and what eligibility typically looks like — written for patients but useful for everyone.

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