Plain-English translation of NCT01273129 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Epilepsy research guide →This trial helps people with drug-resistant epilepsy—seizures that continue despite trying multiple medications—explore surgical treatment options. Doctors will evaluate whether surgery to remove or modify the part of the brain causing seizures might help. The study follows patients through standard surgical procedures that are already approved by the FDA for treating hard-to-control epilepsy.
Many people with epilepsy continue to have seizures even after trying different medications. This trial exists to gather information about how well surgery works for these patients and to better understand how the brain's electrical activity relates to seizure control and thinking.
You likely qualify if…
You likely don't qualify if…
First, neurologists will confirm you have drug-resistant epilepsy through testing. If you qualify, you'll be offered standard diagnostic tests and surgical procedures—which may include brain monitoring with electrodes to pinpoint where your seizures start, followed by surgery to remove or modify that area. All procedures offered are established, FDA-approved treatments for epilepsy; the study documents how well they work and learns more about how your brain functions during and after treatment.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
United States
Enrollment target
~300 participants
Started
March 2011
Age range
8 Years – 99 Years
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Gretchen C Scott, R.N.
National Institute of Neurological Disorders and Stroke (NINDS)
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.