Understanding MS Risk Through Genes and Environment

This large research study is looking for patterns in genetics and environmental factors that might help predict who is at risk of developing multiple sclerosis (MS). Researchers will collect blood samples, stool samples, and health information from about 5,000 people who are at higher risk of developing MS — including people with a family history of MS and people taking certain treatments for other inflammatory diseases. The goal is to build a tool that could one day help doctors identify who might develop MS before symptoms appear.

Multiple sclerosis is an autoimmune disease where the immune system mistakenly attacks the protective coating around nerves, causing serious symptoms. By understanding which genetic and environmental factors increase MS risk, researchers hope to create a better way to predict who might develop the disease and potentially intervene earlier.