Plain-English translation of NCT01441089 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →Researchers know that people respond differently to cancer medications — some get better results, while others experience more side effects. This study collects blood samples from people already enrolled in cancer treatment trials at the National Institutes of Health to analyze genetic differences that may explain these variations. By understanding your genetics, doctors hope to predict who will benefit most from certain medications and who might experience harmful side effects.
Cancer drugs have a narrow margin between an effective dose and a toxic one, and genetic differences can significantly affect how each person's body processes the medication. This research could help doctors personalize cancer treatment in the future by predicting which patients will respond well and which may need different approaches.
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If you qualify, you would donate a blood sample (or a cheek swab if you have leukemia) as part of your existing cancer treatment visits — no extra trips required. Researchers will analyze your DNA to identify genetic variations that might affect how your body processes your cancer medication. If your results show you carry genes linked to poor outcomes or serious side effects with your specific drug, your medical team will receive recommendations to help guide your care.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
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