Exercise to prevent Alzheimer's in at-risk older adults

Researchers studied whether regular aerobic exercise could help control amyloid buildup in the brain and reduce the risk of developing Alzheimer's disease in older adults who already had signs of amyloid deposits but were not yet experiencing memory loss. The trial compared people who exercised regularly for a year to those who followed standard exercise recommendations. The study examined whether exercise could protect brain structure and preserve thinking ability in people at high risk for Alzheimer's.

Alzheimer's disease often develops silently in the brain years before symptoms appear. This trial was designed to test whether catching people early—when amyloid buildup is present but memory is still normal—and having them exercise regularly could slow or prevent the disease from progressing.