Plain-English translation of NCT02091141 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal cancer research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial tested six different targeted cancer medications—including , , , , , , , and —in people with advanced cancers that had specific genetic changes. Each participant received the medication that matched their particular tumor's genetic profile. The study examined whether these treatments were safe and effective when used this way.
Many people with advanced cancer run out of standard treatment options. This trial explored whether matching patients to medications based on their tumor's genetic makeup could offer new hope—giving patients access to drugs designed to work against their specific cancer's molecular characteristics.
Participants received one of six targeted medications based on their tumor's genetic testing results. For intravenous medications, participants visited the clinic every 3 weeks for infusions; for oral medications, participants took pills daily at home on a 28-day cycle. Throughout the trial, participants had regular blood tests, scans, and check-ups to monitor how well the treatment was working and watch for side effects.
AI-generated summary from trial data · Oct 11, 2026 · Not medical advice
United States