Plain-English translation of NCT02824822 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Epilepsy research guide →Researchers at Mayo Clinic want to understand whether some people with epilepsy have hidden genetic heart problems that put them at risk of sudden, unexpected death during or after seizures. This study will collect blood samples and genetic information from adults with epilepsy—especially those at higher risk—and their blood relatives to look for genetic patterns that might explain this risk.
Sudden unexpected death in epilepsy (SUDEP) is a rare but serious complication that doctors don't fully understand. By identifying genetic heart conditions in people with epilepsy, researchers hope to find better ways to predict who is at risk and how to protect them.
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If you qualify, you will be asked to provide a blood sample and possibly a saliva or cheek swab for genetic testing. Researchers will use a risk-scoring tool to assess your seizure-related risk, and they may also ask family members to participate by providing their own samples. The study is still recruiting participants and will enroll approximately 600 people total.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
United States
Sponsor
Mayo Clinic
Collaborators
American Heart Association
Enrollment target
~600 participants
Started
May 2016
Primary completion
December 2031
Age range
18 Years – 50 Years
Last updated on clinicaltrials.gov in September 2025.
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Central contact
Somers CPL Lab
Mayo Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.