Plain-English translation of NCT03135327 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Multiple Sclerosis research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is a two-part study at the University of Miami that uses advanced cameras and imaging equipment to photograph and measure how your eyes work. The first part simply observes and photographs eyes in people with various conditions like multiple sclerosis, dry eye, diabetic retinopathy, and normal healthy eyes over 1–2 years. The second part asks eligible participants to take Ocufolin, an over-the-counter medical food supplement, for 6 months while researchers track whether it helps with certain eye-related changes linked to specific genetic and metabolic factors.
Doctors want to understand how conditions like diabetes, dry eye, and dementia affect the eye's structure and function using the newest imaging technology. This knowledge could help identify people at risk earlier and understand whether nutritional support might help prevent or slow vision problems in people with specific genetic patterns who also have markers of early blood vessel disease in the eyes.
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In the observation phase, you would visit the research clinic to have your eyes photographed and measured using specialized imaging machines (like OCT, which takes detailed pictures of the eye's layers) over 1–2 years, with follow-up appointments. In the optional treatment phase, you would first complete these same baseline eye imaging tests, then take the medical food supplement Ocufolin daily for 6 months while your eyes are re-imaged to see if the supplement creates any measurable changes.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
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