Plain-English translation of NCT03207464 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Multiple Sclerosis research guide →Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
Researchers are testing a new imaging technique called PET to take detailed pictures of the brain and see how multiple sclerosis affects certain nerve cells. This medication is a tracer — a special substance that helps doctors see what's happening inside your brain during the scan. The study compares brain scans from people with MS to healthy volunteers to understand the disease better.
Multiple sclerosis damages nerve cells in the brain and spinal cord, but current imaging methods don't always show this damage clearly. This study hopes to develop a better way to visualize and understand these changes, which could help doctors diagnose MS earlier and track how treatments are working.
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If you join this study, you will undergo two types of brain imaging scans: an MRI scan and a PET scan. Before the PET scan, a small IV line will be placed in your arm to inject the imaging tracer. You'll then lie still in the PET scanner for about two hours (with an optional 20-minute break midway through). The research team will monitor you continuously and you can stop at any time if you feel uncomfortable. You'll also receive an MRI scan, which takes pictures of your brain in a confined tube-like machine.
AI-generated summary from trial data · Jul 10, 2026 · Not medical advice
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