Plain-English translation of NCT03474913 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →This study is testing a new kind of MRI scanner—one where you stand upright instead of lying down flat—to see if it can more accurately detect prostate cancer in men who have elevated PSA levels or concerning symptoms. Researchers hope this new scanning method will reduce unnecessary biopsies and help doctors avoid over-treating cancers that may not be dangerous.
Current PSA blood tests often give false alarms, leading to unnecessary biopsies and treatment of cancers that would never harm you. The traditional ultrasound-guided biopsy can miss real cancers and cause painful complications. This trial exists to see if the new upright MRI scanner can be a better, safer tool to identify which men truly need treatment.
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You will undergo two MRI scans using the new upright scanner. Depending on which group you're assigned to, you may first have a standard MRI as your usual care, then consent to the study and have an upright MRI; or you may consent first and then have both scans done in random order. The study also involves an ultrasound-guided biopsy to help verify the MRI results. The total time commitment and number of visits will depend on your group assignment.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
United States