Plain-English translation of NCT03492424 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →This is an observational study that tracks outcomes in men receiving focal ablation therapy — targeted heat or cold treatments designed to destroy cancer cells in the prostate while preserving healthy tissue. Researchers will collect information about your medical history, treatment details, cancer outcomes (like PSA levels), any side effects, and how the treatment affects your quality of life.
Focal ablation therapies are newer, tissue-sparing alternatives to traditional prostate cancer treatments, but doctors need more real-world data to understand how well these therapies work, which patients benefit most, and what complications can occur. This registry will help doctors make better treatment recommendations for future patients.
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You will have your medical records reviewed before, during, and after your focal ablation treatment. You will be asked to complete questionnaires about your quality of life, urinary function, and sexual function at various time points. Researchers will also track your PSA levels, imaging results, and any side effects or complications you experience over time.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
United States
Collaborators
Prostate Cancer Foundation
Enrollment target
~200 participants
Started
January 2018
Primary completion
March 2032
Age range
18 Years and older
Sex
Male only
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Holly Kuczynsk, BS
Weill Medical College of Cornell University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.