Plain-English translation of NCT03672188 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Hepatitis B research guide →Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial tested , an experimental injectable medication designed to fight chronic hepatitis B infection. Researchers studied the medication in healthy volunteers first to check for safety, then tested it in patients with chronic hepatitis B to see if it could help reduce the virus. The study examined how the body handles the medication and whether it actually works against the virus.
Chronic hepatitis B is a serious infection that can damage the liver over time, and current treatment options don't work well for everyone. This trial was designed to see if this new treatment could offer patients a better way to control the virus.
Healthy volunteers received a single injection under the skin at different dose levels to test safety. Patients with hepatitis B received two injections under the skin, spaced four weeks apart, and were monitored to see how well the medication worked against their virus. Throughout the trial, participants had blood tests and check-ins to track how they responded to the treatment.
AI-generated summary from trial data · Oct 12, 2026 · Not medical advice
Australia
Hong Kong
New Zealand