Plain-English translation of NCT03738072 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Epilepsy research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether using a wider range of electrical stimulation frequencies during a standard brain monitoring procedure can help doctors more accurately identify where seizures begin in people whose epilepsy doesn't respond well to medication. Right now, doctors typically use only two standard frequencies when stimulating the brain during this monitoring. The study will compare results from the standard frequencies against results from new, additional frequencies chosen based on each patient's own seizure patterns and brain activity.
For people with drug-resistant epilepsy who may benefit from surgery, doctors need to pinpoint exactly where in the brain seizures start. The current approach uses only two standard stimulation frequencies without clear scientific evidence that these are the best choices. This trial aims to see whether testing a broader range of frequencies—tailored to each patient's brain and seizure type—could give doctors a clearer, more accurate picture to guide surgery planning.
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If you qualify, you would participate during your scheduled brain monitoring procedure at the hospital. While the electrodes are already in place (as part of your standard medical care), doctors will apply electrical stimulation at both the usual frequencies and additional research frequencies, and record how your brain responds. The study will compare these results to see if the new frequencies provide better information for planning surgery. The entire research component is integrated into your existing medical care over the course of the monitoring period.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
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