Plain-English translation of NCT04035642 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study evaluates a new radiation approach for intermediate-risk prostate cancer called single-dose image-guided radiotherapy. Instead of receiving radiation treatments spread over many weeks, you would receive one carefully targeted, high-dose treatment to your prostate gland in a single session. The doctors use advanced imaging and tracking technology to aim the radiation precisely at the cancer while protecting your urethra (the tube you urinate through) and other nearby organs.
Prostate cancer cells respond very well to large radiation doses given all at once, and doctors have seen good results with this approach in small studies at specialized centers. This trial aims to confirm that this single-dose treatment is safe, works well, and doesn't cause too many side effects when done with careful planning and real-time tracking technology.
You likely qualify if…
You likely don't qualify if…
You would visit the hospital for detailed planning scans (MRI and possibly a PET scan) to map your prostate cancer precisely. On treatment day, a urinary catheter with tracking beacons would be placed, and a rectal balloon would be inserted to keep everything still during treatment. You would then receive your single radiation treatment, which takes about 1–2 hours. After treatment, you would be followed with regular check-ups, blood tests, and imaging to monitor how well the treatment worked and check for any side effects.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
Portugal