Plain-English translation of NCT04083937 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether shorter, more focused radiation therapy schedules can work just as well as traditional longer schedules for prostate cancer patients who need radiation after surgery. Researchers are also comparing two types of radiation — standard photon radiation and proton radiation — to see if proton therapy reduces side effects, particularly bowel irritation.
Traditional radiation therapy for prostate cancer after surgery takes several weeks and can cause bothersome side effects affecting the bowel. This trial exists to see whether delivering higher doses over fewer sessions (called hypofractionation) can shorten treatment while maintaining the same cancer-fighting effectiveness, and whether proton therapy offers better quality of life compared to standard radiation.
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You will be randomly assigned to receive one of three radiation therapy approaches: standard daily radiation over about 7 weeks, or a shorter schedule with higher doses per session (either using standard radiation or proton therapy) over about 3 weeks. You will attend regular appointments for your radiation treatments and follow-up visits to monitor your health, side effects, and PSA levels over time.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
Germany