Plain-English translation of NCT04473794 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Pancreatic Neoplasms research guide →This is a research study that aims to improve how doctors diagnose pancreatic cysts — small fluid-filled pouches that form in the pancreas. Many people have pancreatic cysts found by accident on imaging scans, but doctors struggle to tell which ones are harmless and which ones might become cancer. This study will gather information from 5,000 patients to develop better tools for making that diagnosis.
Right now, doctors cannot reliably tell benign cysts from dangerous ones using standard tests alone, which means some patients get unnecessary surgeries and monitoring while others may not be watched closely enough. This study exists to create a better diagnostic approach that accurately identifies which cysts need treatment and which can be safely left alone.
You likely qualify if…
You likely don't qualify if…
As a participant, you would allow researchers to access your medical records and imaging scans related to your pancreatic cyst. The study does not involve taking medication or undergoing new procedures — instead, it uses information you already have from your doctor's visits and tests. Your involvement helps build a database that doctors can use to better understand and diagnose pancreatic cysts in future patients.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
United States
Sponsor
Johns Hopkins University
Collaborators
National Cancer Institute (NCI)
Enrollment target
~5,000 participants
Started
July 2022
Primary completion
November 2035
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Elham Afghani, MD MPH
Johns Hopkins University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.