Plain-English translation of NCT04603196 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Multiple Sclerosis research guide →Researchers want to understand how common sleep apnea is in people with multiple sclerosis (MS) and whether having both conditions together makes MS worse. This study will ask you to complete a home sleep test and answer questions about your sleep quality and fatigue. The researchers believe that low oxygen during sleep may damage nerve cells in ways that worsen MS progression.
Sleep apnea is very common in people with MS—affecting about 6 in 10 patients—but doctors don't yet know how much this combination affects disease progression or nerve damage. This study aims to measure the true rate of sleep apnea in MS and explore whether treating it could help slow nerve damage.
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You will use a home sleep testing device overnight to check for sleep apnea—similar to wearing a small monitor while you sleep at home. You will also complete questionnaires about your fatigue, sleep quality, and daytime sleepiness. The study may also include blood tests and MRI scans to look for markers of nerve damage. The researchers will compare results between people with MS who have sleep apnea and those who don't.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
United States
Enrollment target
~800 participants
Started
June 2019
Primary completion
June 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in May 2026.
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Central contact
Jacob A Sloane, MD, PhD
Beth Israel Deaconess Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.