Plain-English translation of NCT04806568 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Multiple Sclerosis research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether a computerized cognitive training program called BrainHQ can help improve memory, attention, and thinking skills in people with multiple sclerosis who are experiencing cognitive decline. About 65% of people with MS struggle with these types of cognitive changes, and this research aims to see if targeted brain training—combined with advanced brain imaging—can help rewire the brain and reverse some of this decline.
Memory and thinking problems are very common in MS but are often hard to detect and measure accurately. There are no proven treatments for MS-related cognitive decline yet, so this study is exploring whether brain training can offer a new way to help patients maintain or improve their thinking and memory abilities.
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If you join this study, you will be randomly assigned to either receive computerized brain training or to a control group. Over the course of the study, you will complete multiple visits involving detailed memory and thinking tests, brain imaging scans (MRI), electrical brain recordings (EEG), walking and balance tests, and questionnaires about your daily functioning. You will also use the BrainHQ training program on a computer at home. The study carefully tracks how your brain changes and how your daily activities are affected over time.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
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