Plain-English translation of NCT05022914 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →This study helps doctors find and treat prostate cancer that comes back after surgery. Researchers use a special imaging scan called PSMA PET/CT to locate cancer cells and decide which treatment will work best for each patient. The study also collects blood samples to look for special markers that might help predict how well treatment will work.
After prostate surgery, some men's cancer returns but doctors can't always find where it is with standard imaging. This study tests whether a newer, more sensitive imaging scan can find the cancer earlier and help doctors choose the right treatment—whether that's radiation, surgery, or medication—so patients get the best care faster.
You likely qualify if…
You likely don't qualify if…
You will have a specialized imaging scan (PSMA PET/CT) to find where your cancer may have returned. You will also provide a blood sample so researchers can look for markers that might help predict your treatment outcome. Based on what the scan shows, your doctor will recommend one of several treatment options (radiation, focused radiation, or systemic therapy). The study team will follow your progress to see how well this scanning approach helps guide treatment decisions.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
Italy
Sponsor
Azienda Ospedaliero-Universitaria Careggi
Enrollment target
~180 participants
Started
January 2021
Primary completion
January 2024
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Sex
Male only
Last updated on clinicaltrials.gov in August 2021.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Lorenzo Livi, Prof.
Azienda Ospedaliero-Universitaria Careggi
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.