Plain-English translation of NCT05082181 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Epilepsy research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study tests two different telephone-based support programs designed to help people with epilepsy manage depression and feel better overall. One program, called UPLIFT, teaches you ways to manage depression through changing your thoughts and practices. The other, called BOOST, provides group support from others with epilepsy. Both programs happen over the phone in group sessions, and researchers will track how each one affects your depression, quality of life, and seizures over one year.
People with epilepsy often experience depression, and current treatments don't always work well enough. This trial exists to see whether these telephone-based support programs can help reduce depression and improve how people with epilepsy feel and function in their daily lives.
You likely qualify if…
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You would join either the UPLIFT or BOOST program and attend telephone-based group sessions over 12 months. UPLIFT teaches you strategies to change negative thought patterns and build mental skills, while BOOST focuses on group support and sharing experiences with others who have epilepsy. Throughout the study, researchers will ask you questions about your mood, quality of life, and seizures to see how the program is helping you.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States
Sponsor
NYU Langone Health
Enrollment target
~120 participants
Started
November 2021
Primary completion
August 2027
Age range
18 Years – 99 Years
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Tanya Spruill, PhD
NYU Langone Health
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.