Plain-English translation of NCT05227092 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
Read our Multiple Sclerosis research guide โThis study doesn't follow the usual testing phases โ it may be an observational study or a different type of research.
This trial is testing a new MRI imaging technique called 3D OPTIMIZED WMN MPRAGE to see if it can better detect spinal cord lesions (damage) in people with multiple sclerosis. The new scan will be compared to conventional MRI scans that doctors currently use. If successful, this technique could become the standard way doctors image the spinal cord in MS patients.
About 90% of people with multiple sclerosis have spinal cord involvement, but current MRI scans sometimes miss small lesions or don't show them clearly. This new imaging technique is designed to be more sensitive and accurate, which could help doctors better understand the disease and predict how it will progress.
You likely qualify ifโฆ
You likely don't qualify ifโฆ
You will come in for MRI scans of your cervical (neck) and thoracic (mid-back) spinal cord. During these scans, you'll lie still inside the MRI machine while the new imaging technique and conventional scans are performed. The researchers will compare the images from the new technique to the standard scans to see which one detects spinal cord lesions better.
AI-generated summary from trial data ยท Jun 13, 2026 ยท Not medical advice
France
Sponsor
University Hospital, Bordeaux
Enrollment target
~60 participants
Started
August 2023
Primary completion
May 2026
This trial's estimated completion date has passed โ the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2025.
Reach out to the team running this trial. Response times vary โ some teams are faster than others.
Central contact
Vincent Dousset, MD, PhD
University Hospital, Bordeaux
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first โ no email needed to get started.