Plain-English translation of NCT05313815 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a radiation therapy approach for men diagnosed with high-risk prostate cancer. Participants receive external beam radiation — a type of focused radiation delivered from outside the body — aimed at the prostate and surrounding pelvic area. The treatment uses moderate hypofractionation, which means the total radiation dose is divided into 20 smaller sessions rather than many more sessions, making the schedule shorter than traditional approaches.
Standard radiation therapy for advanced prostate cancer typically requires many more treatment sessions. This trial is testing whether giving the same effective dose in fewer, slightly larger sessions can work just as well while being more convenient for patients.
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You would receive external beam radiation therapy over the course of 20 treatment sessions (typically about 4 weeks). Each session takes place in a hospital or cancer center and involves lying still while a machine directs radiation at your prostate and pelvis. Your doctor may also recommend hormone therapy alongside the radiation, depending on your specific diagnosis. The study will track your health and cancer response over time following treatment.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
Canada
Sponsor
University Health Network, Toronto
Enrollment target
~100 participants
Started
July 2022
Primary completion
April 2030
Age range
18 Years and older
Sex
Male only
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Rachel Glicksman, MD
University Health Network, Toronto
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.