Plain-English translation of NCT05513443 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study compares a newer treatment called irreversible electroporation (IRE) — which uses electrical pulses to destroy cancer cells — against the standard treatments of surgery or radiation for prostate cancer. The trial is designed for men with intermediate-risk prostate cancer that appears in only one spot in the prostate. Researchers want to see if this focused electrical treatment can work as well as traditional approaches while causing fewer side effects on quality of life.
Traditional prostate cancer treatments like surgery and radiation can work well at curing cancer, but they often affect nearby healthy tissues and cause side effects like erectile dysfunction and urinary problems. This trial exists to see whether a more targeted approach using electrical pulses could control cancer just as effectively while preserving quality of life and sexual and urinary function.
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If you join this trial, you will be randomly assigned to either receive the new electrical pulse treatment (IRE) or undergo standard treatment (surgery or radiation). You will have visits with a urologist and oncologist to decide on your treatment plan. The study will track how you recover and your quality of life over time, including sexual and urinary function, with the main evaluation happening 12 months after your treatment. The trial takes place at four hospitals in Stockholm, Sweden.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
Sweden
Sponsor
Karolinska Institutet
Collaborators
Karolinska University Hospital
Enrollment target
~184 participants
Started
September 2022
Primary completion
February 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
40 Years and older
Sex
Male only
Last updated on clinicaltrials.gov in January 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Anna Lantz, Ass Prof
Karolinska University Hospital and Karolinska Institutet
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.