Plain-English translation of NCT05527093 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Epilepsy research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is investigating how epilepsy—particularly drug-resistant epilepsy affecting the temporal lobe—changes the brain's ability to understand other people's emotions, facial expressions, and social behaviors. Researchers will use specialized brain imaging scans to create detailed maps of the brain networks involved in social understanding and see how epilepsy alters these networks. This study aims to fill an important gap: while we know that many epilepsy patients struggle socially, we don't yet fully understand why or how the disease damages these specific brain functions.
Many people with epilepsy experience difficulties understanding social cues and connecting with others, which significantly impacts their quality of life and relationships. However, the exact brain mechanisms causing these social difficulties remain poorly understood. This research aims to create a comprehensive 'map' of how epilepsy damages the brain's social cognition network, which could eventually lead to better treatments and support.
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As a participant, you would undergo specialized brain imaging scans (MRI) designed to examine how your brain processes social information and how epilepsy has affected these networks. You will also complete cognitive and behavioral tests that assess your ability to recognize facial expressions and understand social situations. The study involves one or more visits to the hospital in Paris where these scans and tests are performed as part of your presurgical epilepsy evaluation.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
France