Plain-English translation of NCT05529264 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
Read our Epilepsy research guide โThis study doesn't follow the usual testing phases โ it may be an observational study or a different type of research.
Researchers at Dartmouth-Hitchcock Medical Center want to understand how the brain works and what causes epileptic seizures by safely recording brain signals from people who already have electrodes placed in their brain for medical reasons. The study takes advantage of electrodes that are already surgically inserted to monitor seizures, and asks participants to perform simple tasks while their brain activity is recorded. This research helps scientists learn more about how different parts of the brain communicate and control behavior.
Many people with epilepsy have electrodes placed in their brain as part of their medical care to help doctors find where seizures start. Rather than let this valuable information go unused, researchers want to use these same recordings to study how the healthy brain works and what goes wrong during a seizure. This knowledge could lead to better treatments for epilepsy and other brain conditions in the future.
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If you have intracranial electrodes already placed for medical reasons, researchers will ask you to perform various tasks (like cognitive games or memory exercises) while your brain activity is recorded through those electrodes โ this happens during your hospital stay for clinical evaluation. If you have scalp electrodes, you will similarly perform tasks while your brain waves are recorded non-invasively from the surface of your head. Some participants without any electrodes (healthy volunteers) may complete online tasks or answer questions to help researchers compare results.
AI-generated summary from trial data ยท Jun 19, 2026 ยท Not medical advice
United States