Plain-English translation of NCT05574647 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether doctors can use a faster MRI scan (without contrast dye) instead of the standard longer MRI scan to detect prostate cancer. The trial also compares two different ways of taking prostate tissue samples (biopsies) — one where the doctor estimates needle placement by eye, and another using computer guidance to improve accuracy.
Currently, the NHS uses a longer MRI scan that takes 30–40 minutes and requires an injection of contrast dye. Recent research suggests a shorter, faster scan without dye works just as well, but the evidence isn't strong enough yet to change standard practice. This large trial will provide the high-quality evidence doctors need to decide how to best diagnose prostate cancer in the future.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to receive one of two types of MRI scan — either the standard longer scan with contrast dye or a shorter scan without dye. If your scan shows suspicious areas, you will then be randomly assigned to one of two biopsy methods. One uses visual estimation for needle placement, and the other uses computer image-fusion guidance. The entire process involves hospital visits for scanning and possibly a biopsy procedure, with results reviewed by your clinical team.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
United Kingdom