Plain-English translation of NCT05606523 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Pancreatic Cancer research guide →This research is investigating whether gut bacteria from pancreatic cancer patients who experience severe weight loss might be responsible for that weight loss. Researchers will collect stool samples from three groups: pancreatic cancer patients with significant weight loss, pancreatic cancer patients without weight loss, and healthy volunteers. They will then study these samples in laboratory mice to see if the bacteria from patients with weight loss affects how the mice gain weight.
Many pancreatic cancer patients lose dangerous amounts of weight and muscle even when they are eating enough — a condition called cachexia. This study aims to understand whether changes in gut bacteria might be causing this weight loss, which could eventually lead to new ways to prevent or treat it.
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You will visit the study center once, where researchers will take measurements of your body composition and collect a single stool sample. The visit should take less than an hour. Your sample will then be studied in the laboratory using mice to help researchers understand the link between gut bacteria and cancer-related weight loss. There are no follow-up visits required.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
Switzerland
Sponsor
Genton Graf Laurence
Enrollment target
~24 participants
Started
August 2022
Primary completion
April 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in December 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Laurence Genton Graf, Prof
Geneva University Hospitals (HUG)
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.