Plain-English translation of NCT05657743 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Pancreatic Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new treatment called DaRT Seeds—tiny radioactive implants placed directly into pancreatic tumors to deliver focused radiation therapy. The treatment is designed for people with advanced pancreatic cancer who have already received at least one round of chemotherapy or are too unwell for more chemotherapy, and whose cancer cannot be surgically removed. Researchers want to see if this implant is safe and can help control the cancer.
Advanced pancreatic cancer is very difficult to treat, and many patients either cannot tolerate more chemotherapy or do not qualify for surgery. This trial exists to test whether delivering radiation directly into the tumor through this implant could be a helpful new option for these patients.
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You will first go through a screening period where doctors confirm you are eligible and plan the implant procedure. Then you will have a procedure to place the DaRT Seeds directly into your pancreatic tumor. After that, you will be monitored closely for 4 to 8 weeks with follow-up visits to check for any side effects or problems. The study continues for 3 months total from the time of implant, with additional check-in visits to see how well the treatment is working.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
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