Plain-English translation of NCT05710380 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers at the University of Chicago have developed new software that analyzes prostate MRI images to help doctors spot areas of concern more precisely. This trial is testing whether this software can guide biopsies more accurately, helping doctors find prostate cancer when it's present. If the software works well, it could help future patients get faster, more accurate diagnoses.
Current prostate biopsies sometimes miss cancer or biopsy areas that don't need checking. This trial hopes to show that the new computer software can guide doctors to the right spots, making biopsies more effective and reducing unnecessary testing.
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You will have one MRI scan of your prostate, followed by a guided biopsy where the doctor uses the new software to help select which areas to sample. The research team may collect tissue from up to two extra biopsy targets identified by the software. After that, you'll be followed for about 12 months while researchers monitor your health and results.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
United States
Sponsor
University of Chicago
Collaborators
National Cancer Institute (NCI)
Enrollment target
~180 participants
Started
April 2023
Primary completion
May 2029
Age range
18 Years and older
Sex
Male only
Last updated on clinicaltrials.gov in September 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Aytekin Oto, MD
University of Chicago Medicine Comprehensive Cancer Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.