Intensive treadmill training with balance challenges for multiple sclerosis

This trial is testing whether combining high-intensity treadmill training with balance challenges—where the treadmill surface moves unexpectedly to disrupt your balance—can help people with multiple sclerosis walk better and feel more confident. You'll be randomly assigned to one of four groups to compare different training approaches: some will do intense training with balance challenges, others will do intense training on a stable surface, and others will do moderate-intensity training with or without the balance challenges.

People with multiple sclerosis often struggle with walking speed, endurance, and balance. Research in stroke and spinal cord injury shows that high-intensity training with balance challenges is very effective, and early studies suggest the same approach could help people with MS—but this hasn't been thoroughly tested yet.