Testing a supplement to slow progressive multiple sclerosis

This study is testing whether nicotinamide riboside, a naturally occurring compound related to vitamin B, can help slow the progression of disability in people with progressive multiple sclerosis. Researchers want to know if taking this supplement daily might help protect nerve cells and slow the worsening of MS symptoms over time. This is a phase 2 trial, meaning the medication has shown promise in early testing and now needs to be studied in a larger group of patients.

Progressive multiple sclerosis causes steady worsening of disability over time, and current treatments have limited ability to stop this decline. This trial exists because researchers believe this medication might work differently than existing treatments—potentially by protecting nerve cells and slowing disease progression—offering a new option for people living with this form of MS.