Plain-English translation of NCT05751434 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether regular walking exercise can slow the growth of early-stage prostate cancer in men who are on active surveillance—meaning their cancer is being closely watched but not yet treated with surgery or radiation. About half of participants will be assigned to follow a personalized walking program on a treadmill, guided by an exercise specialist, while the other half will continue their usual exercise habits. Researchers will compare how the two groups' cancer progresses over time.
Many men with low-risk prostate cancer are choosing to delay treatment and instead monitor their cancer carefully. This study exists to find out whether exercise might be a simple, safe way to help slow cancer growth and give men more time before they need surgery or radiation.
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If you join this study, you'll be randomly assigned to either the exercise program or usual care group. Those in the exercise program will meet with an exercise specialist who will design a personalized walking plan using a home treadmill—typically requiring about 150 minutes of walking per week. Both groups will wear a fitness tracker to monitor activity and heart rate, and researchers will check your prostate cancer markers (like PSA levels) at regular intervals to see how the two approaches compare. The study lasts about a year, with periodic check-ins and follow-up appointments.
AI-generated summary from trial data · Aug 8, 2026 · Not medical advice
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