Plain-English translation of NCT05784311 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
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After pancreas surgery (called a Whipple procedure), some patients are at higher risk for serious infections because of bile contamination. This trial compares two antibiotic approaches: standard antibiotics given during surgery only, versus extended treatment with and for five days after surgery. The study aims to see if the longer course of the medication reduces dangerous infections in the surgical area.
Doctors aren't sure whether giving antibiotics for several days after this type of surgery actually helps prevent infections compared to standard care. Different hospitals use different approaches, and the medical community needs clear evidence to guide the best practice.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to one of two groups when you come for your Whipple procedure. One group receives antibiotics only during and immediately after surgery (standard care). The other group receives the same surgical antibiotics plus additional antibiotic doses ( and ) three times daily for five days after surgery. Researchers will follow you for 90 days after surgery to check for any infections in the surgical area and track how you heal.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
Netherlands