Plain-English translation of NCT05796973 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Prostate Cancer research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This clinical trial is testing whether supervised group exercise — with or without the medication — can help advanced breast, prostate, kidney, or ovarian cancer respond better to standard cancer drugs. The researchers believe that exercise may help reduce low-oxygen conditions in tumors that help cancer cells survive, and that may work together with exercise to block cancer cells' ability to accumulate fats they need to grow.
Advanced cancers often develop low-oxygen environments that help them hide from the immune system and spread more aggressively. This trial exists to test whether exercise and cholesterol-lowering treatment can work together to change these conditions in tumors and make standard cancer drugs more effective.
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You will be randomly assigned to one of three groups for 3 months: supervised group exercise twice weekly, supervised exercise plus daily , or voluntary unsupervised exercise. At the start, end, and 6 months after the program, your fitness level and body composition will be measured. The exercise program includes both aerobic training and strength training, and you'll be encouraged to keep exercising regularly after the 3-month intervention ends.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
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