Plain-English translation of NCT05865561 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Epilepsy research guide →Researchers are investigating whether people with epilepsy release specific odors—called volatile organic compounds—that could signal when a seizure is about to occur. The study builds on evidence from trained seizure-alert dogs that can detect these odors. By collecting and analyzing breath and body odor samples from people during video-EEG monitoring, the research team hopes to develop a non-invasive way to predict seizures before they happen.
Epileptic seizures are unpredictable and cause significant stress and safety concerns for people living with epilepsy. If researchers can identify reliable odor patterns that signal an incoming seizure, doctors could eventually help patients prevent falls and injuries, allow some people to drive safely, and reduce emergency medical costs.
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You will spend at least 48 hours in the hospital undergoing video-EEG monitoring, which records your brain activity while cameras capture any seizures. During this time, researchers will collect samples of your breath and body odors to analyze for chemical patterns associated with seizures. The study is observational, meaning you won't receive a new medication—just standard monitoring combined with odor sample collection to help scientists understand whether these natural body signals can predict seizures.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
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