Plain-English translation of NCT06040125 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our PROSTATE CANCER research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is a pilot study testing whether a 16-week supervised exercise program can help men with advanced prostate cancer maintain their strength and physical function while receiving hormone therapy. Researchers want to understand whether exercise can prevent or reduce the weakness and muscle loss that often happen as a side effect of this treatment. Half of participants will do the exercise program, and half will continue their normal activities.
Men receiving long-term hormone therapy for advanced prostate cancer often develop weakness, frailty, and loss of muscle mass that can affect their quality of life and independence. This study exists to see whether a tailored exercise program can help prevent these problems and help men stay stronger during treatment.
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If you join this study, you will be randomly assigned to either the exercise group or the comparison group. The exercise group will attend supervised exercise sessions for 16 weeks, while the comparison group will continue their normal daily activities. Both groups will complete fitness tests, muscle biopsies, blood tests, and surveys at the beginning and end of the study to measure changes in strength and muscle. Your total participation will last about 16 weeks.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
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