Plain-English translation of NCT06105645 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Epilepsy research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
If you have drug-resistant epilepsy, you may be considering brain surgery. This trial is testing whether monitoring a specific type of brain activity — called fast-ripples — can help your doctors decide if surgery is right for you and where to operate. Researchers will compare two groups: one group gets special hybrid electrodes that can detect fast-ripples, and another group gets standard electrodes without this extra information.
Many people with drug-resistant epilepsy benefit from surgery, but doctors don't always know exactly which part of the brain is causing seizures. This study is testing whether detecting fast-ripples — rare, very-fast brain signals — can give doctors better information to plan safer and more effective surgery.
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You will undergo a diagnostic brain monitoring procedure (SEEG) that your doctors already recommended. If you're in the test group, 4 to 6 of your standard electrodes will be replaced with special hybrid electrodes that detect fast-ripples. Researchers will record your brain activity during rest and sleep over about one week. Your brain recordings will be analyzed by a research team, and the results will be shared with your doctors before your surgery planning meeting to help guide their decision about whether surgery is right for you.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
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