Plain-English translation of NCT06221631 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Multiple Sclerosis research guide →Researchers want to understand how multiple sclerosis affects how quickly the brain ages compared to healthy people. This study will collect blood samples, perform clinical exams, and use advanced brain imaging to measure biological age and look for signs of brain aging in both healthy volunteers and people with MS.
Multiple sclerosis is a condition that causes inflammation in the brain and nervous system, and doctors want to know whether this speeds up brain aging. By comparing healthy people to those with MS, researchers hope to develop better ways to measure and potentially slow brain aging in MS patients.
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You will visit the hospital for one study appointment where you'll give a blood sample for biological age testing, complete a clinical exam to check your movement and thinking abilities, and undergo an advanced MRI scan of your brain. The entire visit will take several hours. Healthy volunteers will have a quick screening based on their blood results to confirm they qualify before completing the full visit.
AI-generated summary from trial data · Jul 13, 2026 · Not medical advice
Switzerland
Sponsor
Insel Gruppe AG, University Hospital Bern
Collaborators
Schweizerische Multiple Sklerose Gesellschaft, University of Bern
Enrollment target
~200 participants
Started
August 2024
Primary completion
March 2028
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Alejandro X. León Betancourt, Dr.med.
Head of the MS outpatient clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.